Vernal Keratoconjunctivitis and Severe Keratoconus Associated with Autoimmune Polyglandular Syndrome Type II (APS-2); A Case Report

Hussam H AlHawari, Muawyah D Al Bdour


Vernal keratoconjunctivitis (VKC) is a bilateral, usually seasonally recurrent inflammation of the conjunctiva. Even though it is an uncommon type of allergic eye disease but in some cases it can cause severe damage to the ocular surface, leading to keratoconus (KC) and vision loss. We report a rare case of vernal keratoconjunctivitis and keratoconus diagnosed since childhood and then was diagnosed years later with Addison's disease and subclinical hypothyroidism. Even though the association between VKC and autoimmune diseases is still not clear but this case highlights the importance of having a low threshold to screen patients with VKC for autoimmune diseases based on their clinical presentation.


Addison’s disease; hypothyroidism; keratoconus; autoimmune polyglandular syndrome, type II; vernal keratoconjuctivitis.


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