Pharmacogenetics: Fitting the Drug to the Patient "Medical Horizons"

Aly A. Misha'l


For many years, physicians have noticed variable effectiveness of drugs when prescribed to different patients. Side effects of the same drugs have been also noticed to vary among patients.

The prevailing concept that taking drugs is invariably beneficial and safe, is being challenged by the experience from various parts of the world pointing to limited efficacy, and even hazardous effects, of many drugs, when used in different individuals and from different ethnicities. Not all individuals benefit from treatment. Some patients may not benefit at all from existing drugs, and others may suffer serious adverse reactions.

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