Giant Cell Angiofibroma of Oral Cavity

Hunaina Al-kindi, Mina George, Mohammed Al-Harthi


To present a case of a 23-year-old male complaining of slow growing left cheek swelling of 8 months duration which was excised. .
Giant cell angiofibroma is a rare distinctive benign slow growing soft tissue neoplasm which most often involves the orbital region and eyelids of middle-aged adults. It has also been observed in the oral cavity
Histopathology of this tumour shows bland, oval to spindle cells set in a collagenous or myxoid stroma with multinucleated giant cells and angiectoid spaces. Characteristically the mononuclear cell and multinucleated stromal cells are positive for CD34, CD99 and less frequently BCL2.
This is a rare case of giant cell angiofibroma involving the oral cavity

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