Capsule Endoscopy: Single Center Experience

Abdullah Alyouzbaki, Doaa Khadomi, Sara Haj Ali, M. Amer Khatib, Mustafa M. Shennak, Awni Abu sneineh


Objective: Capsule endoscopy (CE) has revolutionized the evaluation of small bowel disorders, particularly obscure gastrointestinal bleeding (OGIB). The aim of this study was to determine the findings and the diagnostic yield of CE in a large series of patients with suspected small bowel disease mainly OGIB; as well as to compare our results to that of other reported centers.

Methods: Data on 230 patients who underwent capsule endoscopy for suspected small bowel related symptoms and/ or signs mainly overt (81 patients) or occult (66 patients) OGIB were obtained by retrospective chart review and review of an internal computer database of capsule endoscopy patients. Data presented as percentages, p value used to show differences whenever relevant.

Results: Out of 230 patients investigated for small bowel related symptoms and /or signs, 7 patients excluded mainly due to improper preparation, of the remaining 223, 128 (57.3%) had some lesion detected by CE,80 (35.8%) had definite lesions detected that could unequivocally explain patients' complaints. Patients with overt GI bleeding had the highest diagnostic yield (64.1%), this was significantly greater (P < 0.001) compared to that in patients with occult bleeding (43.9%) as well as those with abdominal pain and/or diarrhea (33.3%). Angiodysplasia is the most common cause of OGIB (26.5%).

Conclusions: The yield of clinically important findings on CE in patients with OGIB is 55% and is greater in patients with obscure-overt than obscure-occult GI bleeding. Angiodysplasia account for the majority of significant lesions in both groups.


Capsule endoscopy, Gastrointestinal bleeding.

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