Folic Acid Treatment of Hyperhomocysteinemia in Dialysis Patients

Ahmad Al- Marafi, Ali Al-Ghuweri


Objectives: We examined the effect of Folic Acid (FA) administration on the homocysteine level of chronic hemodialysis patients.

Methods: The study group included 16 patients (11 male and 5 female) with CRF; their ages ranged from 20 to 57 years, who were undergoing dialysis at the dialysis unit of Zaid Bin AI-Hussein Hospital in Jordan (2004/2005).

Results: (Hcy) level, of patients' group after supplementation with (FA) led to a significant decrease in homocysteine level (39.7%), (p<0.001),while no significant difference in homocysteine level was shown in control patients .

Conclusion: Supplementation of the diet with (FA), at levels above the current recommended dietary allowances, reduces elevated homocysteine levels in (CRF) patients.


Homocysteine (Hcy), Folic Acid (FA), Chronic Renal Failure (CRF)

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