Comparison Between Frequencies of Several STRs Loci in Jordan with Neighboring Countries

Mohammed Azab, Nabil AL-Bashir, Susan N. Momani, Amjad Al-Nasser, Almuthanna K. Alkaraki, Omar F. Khabour

Abstract


Objective: To investigate the frequencies of 9 autosomal Short Tandem Repeats (STR) loci in the Jordanian population and compare them with the frequencies in neighboring countries.

Methods: DNA was extracted from the blood of 270 unrelated Jordanian individuals. CSFIPO, TPOX, THO1, F13AO1, FESFPS, vWA, D16S539, D7S820, D13S317 Markers were detected by amplifying the extracted genomic DNA using GenePrint™ STR Multiplex system.

Results: For each Marker, 6-9 alleles were observed. Markers D7S820 and D13S317 had the highest Power of Discrimination (PD) values while TPOX was the least informative marker. Marker D16S539 is significantly different in Jordanian population compared to all other neighboring populations.

Conclusion: Marker D16S539 is very powerful for discriminating between Jordanian and other populations from neighboring countries. The combination between these 9 SRS loci seems to be a powerful tool for individual identification in the region.

Keywords


Short tandem repeat (STR); Population data; Allele frequencies; Jordanian

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