Herpes Gestations: A Case Report

Ashraf Al-Nawafleh, Taghreed Al-Maeteh

Abstract


A 34 year old female, presented to our dermatology clinic with pruritic polymorphous vesicles, papules and bullae during her 16 week of pregnancy which was the sixth pregnancy. She was diagnosed on clinical and histopathoogical bases to have "Herpes Gestations.” There was no previous history of Herpes Gestations (H.G) in previous pregnancies. She was started on prednisolone 5mgm/tablet, 30 mgm daily, which led into lesion clearing.
She delivered a normal baby and the steroid was tapered and then was stopped two weeks after delivery.
The importance of this presentation is to keep in mind the possibility of the occurrence of this disease during pregnancy.
Case Report
A 34-year – old pregnant woman, who is gravida 6 para 4 + one abortion, presented to our dermatology clinic with pruritic polymorphous vesiculo bullous lesions that started at the 16th week gestation. It appeared first on the umbilicus then spread as erythematous annular over the extremities including palms and soles. Laboratory investigations showed normal data, but a direct immunoflourescence studies showed a C3 deposition at the basement membrance zone.
The patient was started on prednisolone 5mgm/tab, 30mgm daily, which cleared all lesions. The steroid was tapered and discontinued two weeks after delivery. The baby was born normal and the mother too. There was no recurrence of the lesion.
Herpes Gestations is pruritic inflammatory bullous disease with onset either during pregnancy or during the post partum period.
Its incidence is 1 in 50,000 pregnancies, the onset of the disease is most often during the second trimester, it starts with urticarial papules, plagues, and anular lesions around the umbilicus and spread to the extrimities, then to the abdomen, back and chest. It’s associated with severe itching, the usual outcome of both the infant and mother is normal.
Herpes gestations is an autoimmune disease there is increased frequency of HLA – DR 3.
The treatment is successful with the use of steroid in both topical and systemic forms our case report was A34 – year old pregnant women, presented with pruritic polymosphous vesiculo bullous lesion that started at the 16th week of gestation. It appeared first on the umbilicus then spread as erythematous annular over the extremities laboratory investigation which showed normal data. The patient was treated with steriod which cleared all lesions the baby was born normal and the mother too.

Keywords


Herpes Gestations.

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