Folic Acid Treatment of Hyperhomocysteinemia in Dialysis Patients

Ahmad Al- Marafi, Ali Al-Ghuweri

Abstract


Objectives: We examined the effect of Folic Acid (FA) administration on the homocysteine level of chronic hemodialysis patients.

Methods: The study group included 16 patients (11 male and 5 female) with CRF; their ages ranged from 20 to 57 years, who were undergoing dialysis at the dialysis unit of Zaid Bin AI-Hussein Hospital in Jordan (2004/2005).

Results: (Hcy) level, of patients' group after supplementation with (FA) led to a significant decrease in homocysteine level (39.7%), (p<0.001),while no significant difference in homocysteine level was shown in control patients .

Conclusion: Supplementation of the diet with (FA), at levels above the current recommended dietary allowances, reduces elevated homocysteine levels in (CRF) patients.

Keywords


Homocysteine (Hcy), Folic Acid (FA), Chronic Renal Failure (CRF)

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